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Another study reported that, in children with fever, the area under the serum concentration-time curve (AUC) increased by 13–44% from first dose to steady state implying that paracetamol may accumulate in this patient group although no ‘hepatotoxicity’ was demonstrated [48]

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Interleukin-4- and interleukin-13-mediated alternatively activated macrophages: roles in homeostasis and disease